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Aqumeldi® (enalapril maleate)

About Aqumeldi®

Aqumeldi (enalapril maleate) 0.25 mg orodispersible tablets

Aqumeldi is indicated for the treatment of heart failure in children from birth to less than 18 years.1

Aqumeldi is a novel formulation and the first and only paediatric-licensed enalapril for heart failure — because children are not just small adults.2-4

Mini-ODT: mini orodispersible tablet

How can you order Aqumeldi?

Aqumeldi is available as a prescription only medicine (POM).

Aqumeldi can be ordered in bottle size of 50 or 100 tablets from Alliance Healthcare.

Item size: 50 tablets
Pip Code: 428-0988

Item size: 100 tablets
Pip Code: 428-0970

Please refer to the SmPC for full details on the product.

Aqumeldi is recommended in 1 or 2 divided doses per day1

Aqumeldi is the first and only paediatric-licensed enalapril for the treatment of heart failure in children from birth to less than 18 years1

Aqumeldi — dedicated paediatric clinical studies in HF establishing its safety profile over a duration of 1 year1,5

Aqumeldi is a novel paediatric formulation — a mini ODT that rapidly disperses in the mouth2

Aqumeldi is readily available in a low dose strength (0.25 mg) — enabling accurate titration and dose adjustments1,2

Please see information below to report adverse events in the UK

Adverse events should be reported. Reporting forms and information can be found at: www.mhra.gov.uk/yellowcard.
Adverse events should also be reported to Proveca Limited.
Phone: +44 333 200 1866 E-mail: medinfo@proveca.com

References

  1. Aqumeldi Summary of Product Characteristics (January 2024)
  2. Bajcetic, M., et al. (2019). Orodispersible mini tablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety study. Contemp Clin Trials Commun. 15(100393)
  3. Klassen, T. P., et al., (2008). Children are not just small adults: The urgent need for high-quality trial evidence in children PLOS Medicine. Vol 5(8):e172
  4. British National Formulary for Children (BNFC). Enalapril maleate. Available from: https://bnfc.nice.org.uk/drugs/enalapril-maleate
  5. Data on file
  6. Dexcel Pharma Ltd enalapril maleate 2.5 mg Summary of Product Characteristics, (December 2021)  Available Online: https://www.medicines.org.uk/emc/product/2666/smpc
  7. Dexcel Pharma Ltd enalapril maleate 5 mg Summary of Product Characteristics, (December 2021)  Available Online: https://www.medicines.org.uk/emc/product/2671/smpc

All references Last accessed: April 2024

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